diff --git a/Marlin/src/inc/Conditionals_adv.h b/Marlin/src/inc/Conditionals_adv.h
index edee5e9bd2..3a3daa84ac 100644
--- a/Marlin/src/inc/Conditionals_adv.h
+++ b/Marlin/src/inc/Conditionals_adv.h
@@ -1133,6 +1133,9 @@
   #endif
 #endif
 
+// Test for edge stepping on any axis
+#define AXIS_HAS_DEDGE(A) (ENABLED(EDGE_STEPPING) && AXIS_IS_TMC(A))
+
 #if ENABLED(DIRECT_STEPPING)
   #ifndef STEPPER_PAGES
     #define STEPPER_PAGES 16
diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index 84118729a2..30b5963e44 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -4313,6 +4313,40 @@ static_assert(_PLUS_TEST(4), "HOMING_FEEDRATE_MM_M values must be positive.");
   #error "MONITOR_DRIVER_STATUS and SDSUPPORT cannot be used together on boards with shared SPI."
 #endif
 
+// Although it just toggles STEP, EDGE_STEPPING requires HIGH state for logic
+#if ENABLED(EDGE_STEPPING)
+  #if AXIS_HAS_DEDGE(X) && STEP_STATE_X != HIGH
+    #error "STEP_STATE_X must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(Y) && STEP_STATE_Y != HIGH
+    #error "STEP_STATE_Y must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(Z) && STEP_STATE_Z != HIGH
+    #error "STEP_STATE_Z must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(I) && STEP_STATE_I != HIGH
+    #error "STEP_STATE_I must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(J) && STEP_STATE_J != HIGH
+    #error "STEP_STATE_J must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(K) && STEP_STATE_K != HIGH
+    #error "STEP_STATE_K must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(U) && STEP_STATE_U != HIGH
+    #error "STEP_STATE_U must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(V) && STEP_STATE_V != HIGH
+    #error "STEP_STATE_V must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(W) && STEP_STATE_W != HIGH
+    #error "STEP_STATE_W must be HIGH for EDGE_STEPPING."
+  #endif
+  #if AXIS_HAS_DEDGE(E0) && STEP_STATE_E != HIGH
+    #error "STEP_STATE_E must be HIGH for EDGE_STEPPING."
+  #endif
+#endif
+
 // G60/G61 Position Save
 #if SAVED_POSITIONS > 256
   #error "SAVED_POSITIONS must be an integer from 0 to 256."
diff --git a/Marlin/src/module/stepper/trinamic.h b/Marlin/src/module/stepper/trinamic.h
index 3705543c99..88c0686fc3 100644
--- a/Marlin/src/module/stepper/trinamic.h
+++ b/Marlin/src/module/stepper/trinamic.h
@@ -115,8 +115,6 @@
 void restore_trinamic_drivers();
 void reset_trinamic_drivers();
 
-#define AXIS_HAS_DEDGE(A) (AXIS_IS_TMC(A) && ENABLED(EDGE_STEPPING))
-
 // X Stepper
 #if AXIS_IS_TMC(X)
   extern TMC_CLASS(X, X) stepperX;