diff --git a/BaseTools/Plugin/CodeQL/analyze/globber.py b/BaseTools/Plugin/CodeQL/analyze/globber.py
index 5d45abaa1f..db8cda595e 100644
--- a/BaseTools/Plugin/CodeQL/analyze/globber.py
+++ b/BaseTools/Plugin/CodeQL/analyze/globber.py
@@ -34,7 +34,7 @@
 import re
 
 _double_star_after_invalid_regex = re.compile(r'[^/\\]\*\*')
-_double_star_first_before_invalid_regex = re.compile('^\\*\\*[^/]')
+_double_star_first_before_invalid_regex = re.compile(r'^\\*\\*[^/]')
 _double_star_middle_before_invalid_regex = re.compile(r'[^\\]\*\*[^/]')
 
 
diff --git a/BaseTools/Scripts/ConvertFceToStructurePcd.py b/BaseTools/Scripts/ConvertFceToStructurePcd.py
index 9e7fe58768..4c281e9173 100644
--- a/BaseTools/Scripts/ConvertFceToStructurePcd.py
+++ b/BaseTools/Scripts/ConvertFceToStructurePcd.py
@@ -89,12 +89,12 @@ class parser_lst(object):
     return structs_file
 
   def struct(self):#struct:{offset:name}
-    unit_num = re.compile('(\d+)')
-    offset1_re = re.compile('(\d+)\[')
-    pcdname_num_re = re.compile('\w+\[(\S+)\]')
-    pcdname_re = re.compile('\](.*)\<')
-    pcdname2_re = re.compile('(\w+)\[')
-    uint_re = re.compile('\<(\S+)\>')
+    unit_num = re.compile(r'(\d+)')
+    offset1_re = re.compile(r'(\d+)\[')
+    pcdname_num_re = re.compile(r'\w+\[(\S+)\]')
+    pcdname_re = re.compile(r'\](.*)\<')
+    pcdname2_re = re.compile(r'(\w+)\[')
+    uint_re = re.compile(r'\<(\S+)\>')
     name_format = re.compile(r'(?<!typedef)\s+struct (\w+) {.*?;', re.S)
     name=name_format.findall(self.text)
     info={}
@@ -214,8 +214,8 @@ class Config(object):
 
   #Parser .config file,return list[offset,name,guid,value,help]
   def config_parser(self):
-    ids_re =re.compile('_ID:(\d+)',re.S)
-    id_re= re.compile('\s+')
+    ids_re =re.compile(r'_ID:(\d+)',re.S)
+    id_re= re.compile(r'\s+')
     info = []
     info_dict={}
     with open(self.config, 'r') as text:
@@ -435,7 +435,7 @@ class PATH(object):
 
   def header(self,struct):
     header={}
-    head_re = re.compile('typedef.*} %s;[\n]+(.*)(?:typedef|formset)'%struct,re.M|re.S)
+    head_re = re.compile(r'typedef.*} %s;[\n]+(.*)(?:typedef|formset)'%struct,re.M|re.S)
     head_re2 = re.compile(r'#line[\s\d]+"(\S+h)"')
     for i in list(self.lstinf.keys()):
       with open(i,'r') as lst:
diff --git a/BaseTools/Scripts/PackageDocumentTools/plugins/EdkPlugins/basemodel/efibinary.py b/BaseTools/Scripts/PackageDocumentTools/plugins/EdkPlugins/basemodel/efibinary.py
index 1bc4938bfc..856d97b510 100644
--- a/BaseTools/Scripts/PackageDocumentTools/plugins/EdkPlugins/basemodel/efibinary.py
+++ b/BaseTools/Scripts/PackageDocumentTools/plugins/EdkPlugins/basemodel/efibinary.py
@@ -528,7 +528,7 @@ class EfiSectionHeader(BinaryItem):
 
 
 
-rMapEntry = re.compile('^(\w+)[ \(\w\)]* \(BaseAddress=([0-9a-fA-F]+), EntryPoint=([0-9a-fA-F]+), GUID=([0-9a-fA-F\-]+)')
+rMapEntry = re.compile(r'^(\w+)[ \(\w\)]* \(BaseAddress=([0-9a-fA-F]+), EntryPoint=([0-9a-fA-F]+), GUID=([0-9a-fA-F\-]+)')
 class EfiFvMapFile(object):
     def __init__(self):
         self._mapentries = {}
diff --git a/BaseTools/Scripts/PatchCheck.py b/BaseTools/Scripts/PatchCheck.py
index a3b812fb73..9d398170fe 100755
--- a/BaseTools/Scripts/PatchCheck.py
+++ b/BaseTools/Scripts/PatchCheck.py
@@ -237,7 +237,7 @@ class CommitMessageCheck:
             if sigtype == 'Cc' and len(sigs) == 0:
                 self.error('No Cc: tags for maintainers/reviewers found!')
 
-    cve_re = re.compile('CVE-[0-9]{4}-[0-9]{5}[^0-9]')
+    cve_re = re.compile(r'CVE-[0-9]{4}-[0-9]{5}[^0-9]')
 
     def check_overall_format(self):
         lines = self.msg.splitlines()
diff --git a/BaseTools/Source/Python/Common/GlobalData.py b/BaseTools/Source/Python/Common/GlobalData.py
index 11849e863f..1853de1d11 100755
--- a/BaseTools/Source/Python/Common/GlobalData.py
+++ b/BaseTools/Source/Python/Common/GlobalData.py
@@ -54,7 +54,7 @@ gHexPattern = re.compile(r'0[xX]{}+'.format(_HexChar))
 gHexPatternAll = re.compile(r'0[xX]{}+$'.format(_HexChar))
 
 ## Regular expressions for string identifier checking
-gIdentifierPattern = re.compile('^[a-zA-Z][a-zA-Z0-9_]*$', re.UNICODE)
+gIdentifierPattern = re.compile(r'^[a-zA-Z][a-zA-Z0-9_]*$', re.UNICODE)
 ## Regular expression for GUID c structure format
 _GuidCFormatPattern = r"{{\s*0[xX]{Hex}{{1,8}}\s*,\s*0[xX]{Hex}{{1,4}}\s*,\s*0[xX]{Hex}{{1,4}}" \
                       r"\s*,\s*{{\s*0[xX]{Hex}{{1,2}}\s*,\s*0[xX]{Hex}{{1,2}}" \
diff --git a/BaseTools/Source/Python/Common/Misc.py b/BaseTools/Source/Python/Common/Misc.py
index 34bfc90abd..aa89bf9cda 100755
--- a/BaseTools/Source/Python/Common/Misc.py
+++ b/BaseTools/Source/Python/Common/Misc.py
@@ -1926,4 +1926,4 @@ def CopyDict(ori_dict):
 # Remove the c/c++ comments: // and /* */
 #
 def RemoveCComments(ctext):
-    return re.sub('//.*?\n|/\\*.*?\\*/', '\n', ctext, flags=re.S)
+    return re.sub(r'//.*?\n|/\\*.*?\\*/', '\n', ctext, flags=re.S)
diff --git a/BaseTools/Source/Python/Common/StringUtils.py b/BaseTools/Source/Python/Common/StringUtils.py
index 73dafa797a..4b34d8fa06 100644
--- a/BaseTools/Source/Python/Common/StringUtils.py
+++ b/BaseTools/Source/Python/Common/StringUtils.py
@@ -21,7 +21,7 @@ from CommonDataClass.Exceptions import *
 from Common.LongFilePathSupport import OpenLongFilePath as open
 from Common.MultipleWorkspace import MultipleWorkspace as mws
 
-gHexVerPatt = re.compile('0x[a-f0-9]{4}[a-f0-9]{4}$', re.IGNORECASE)
+gHexVerPatt = re.compile(r'0x[a-f0-9]{4}[a-f0-9]{4}$', re.IGNORECASE)
 gHumanReadableVerPatt = re.compile(r'([1-9][0-9]*|0)\.[0-9]{1,2}$')
 
 ## GetSplitValueList
diff --git a/BaseTools/Source/Python/Ecc/Check.py b/BaseTools/Source/Python/Ecc/Check.py
index 33060db5f2..9f95b72cf9 100644
--- a/BaseTools/Source/Python/Ecc/Check.py
+++ b/BaseTools/Source/Python/Ecc/Check.py
@@ -1112,7 +1112,7 @@ class Check(object):
             RecordSet = EccGlobalData.gDb.TblInf.Exec(SqlCommand)
             for Record in RecordSet:
                 Path = Record[1]
-                Path = Path.upper().replace('\X64', '').replace('\IA32', '').replace('\EBC', '').replace('\IPF', '').replace('\ARM', '')
+                Path = Path.upper().replace('\\X64', '').replace('\\IA32', '').replace('\\EBC', '').replace('\\IPF', '').replace('\\ARM', '')
                 if Path in InfPathList:
                     if not EccGlobalData.gException.IsException(ERROR_META_DATA_FILE_CHECK_MODULE_FILE_NO_USE, Record[2]):
                         EccGlobalData.gDb.TblReport.Insert(ERROR_META_DATA_FILE_CHECK_MODULE_FILE_NO_USE, OtherMsg="The source file [%s] is existing in module directory but it is not described in INF file." % (Record[2]), BelongsToTable='File', BelongsToItem=Record[0])
diff --git a/BaseTools/Source/Python/Ecc/Configuration.py b/BaseTools/Source/Python/Ecc/Configuration.py
index 9d9feaca5e..ae2ebf30b9 100644
--- a/BaseTools/Source/Python/Ecc/Configuration.py
+++ b/BaseTools/Source/Python/Ecc/Configuration.py
@@ -435,7 +435,7 @@ class Configuration(object):
 # test that our dict and out class still match in contents.
 #
 if __name__ == '__main__':
-    myconfig = Configuration("BaseTools\Source\Python\Ecc\config.ini")
+    myconfig = Configuration("BaseTools\\Source\\Python\\Ecc\\config.ini")
     for each in myconfig.__dict__:
         if each == "Filename":
             continue
diff --git a/BaseTools/Source/Python/Ecc/MetaFileWorkspace/MetaFileParser.py b/BaseTools/Source/Python/Ecc/MetaFileWorkspace/MetaFileParser.py
index 2d98ac5ead..00a80a3f41 100644
--- a/BaseTools/Source/Python/Ecc/MetaFileWorkspace/MetaFileParser.py
+++ b/BaseTools/Source/Python/Ecc/MetaFileWorkspace/MetaFileParser.py
@@ -1841,14 +1841,14 @@ class DecParser(MetaFileParser):
 
         if EccGlobalData.gConfig.UniCheckPCDInfo == '1' or EccGlobalData.gConfig.UniCheckAll == '1' or EccGlobalData.gConfig.CheckAll == '1':
             # check Description, Prompt information
-            PatternDesc = re.compile('##\s*([\x21-\x7E\s]*)', re.S)
-            PatternPrompt = re.compile('#\s+@Prompt\s+([\x21-\x7E\s]*)', re.S)
+            PatternDesc = re.compile(r'##\s*([\x21-\x7E\s]*)', re.S)
+            PatternPrompt = re.compile(r'#\s+@Prompt\s+([\x21-\x7E\s]*)', re.S)
             Description = None
             Prompt = None
             # check @ValidRange, @ValidList and @Expression format valid
             ErrorCodeValid = '0x0 <= %s <= 0xFFFFFFFF'
-            PatternValidRangeIn = '(NOT)?\s*(\d+\s*-\s*\d+|0[xX][a-fA-F0-9]+\s*-\s*0[xX][a-fA-F0-9]+|LT\s*\d+|LT\s*0[xX][a-fA-F0-9]+|GT\s*\d+|GT\s*0[xX][a-fA-F0-9]+|LE\s*\d+|LE\s*0[xX][a-fA-F0-9]+|GE\s*\d+|GE\s*0[xX][a-fA-F0-9]+|XOR\s*\d+|XOR\s*0[xX][a-fA-F0-9]+|EQ\s*\d+|EQ\s*0[xX][a-fA-F0-9]+)'
-            PatternValidRng = re.compile('^' + '(NOT)?\s*' + PatternValidRangeIn + '$')
+            PatternValidRangeIn = r'(NOT)?\s*(\d+\s*-\s*\d+|0[xX][a-fA-F0-9]+\s*-\s*0[xX][a-fA-F0-9]+|LT\s*\d+|LT\s*0[xX][a-fA-F0-9]+|GT\s*\d+|GT\s*0[xX][a-fA-F0-9]+|LE\s*\d+|LE\s*0[xX][a-fA-F0-9]+|GE\s*\d+|GE\s*0[xX][a-fA-F0-9]+|XOR\s*\d+|XOR\s*0[xX][a-fA-F0-9]+|EQ\s*\d+|EQ\s*0[xX][a-fA-F0-9]+)'
+            PatternValidRng = re.compile(r'^' + r'(NOT)?\s*' + PatternValidRangeIn + '$')
             for Comment in self._Comments:
                 Comm = Comment[0].strip()
                 if not Comm:
@@ -2071,7 +2071,7 @@ class UniParser(object):
     def CheckKeyValid(self, Key, Contents=None):
         if not Contents:
             Contents = self.FileIn
-        KeyPattern = re.compile('#string\s+%s\s+.*?#language.*?".*?"' % Key, re.S)
+        KeyPattern = re.compile(r'#string\s+%s\s+.*?#language.*?".*?"' % Key, re.S)
         if KeyPattern.search(Contents):
             return True
         return False
diff --git a/BaseTools/Source/Python/Ecc/c.py b/BaseTools/Source/Python/Ecc/c.py
index 61ad084fcc..0ebdc1a996 100644
--- a/BaseTools/Source/Python/Ecc/c.py
+++ b/BaseTools/Source/Python/Ecc/c.py
@@ -43,7 +43,7 @@ def GetArrayPattern():
     return p
 
 def GetTypedefFuncPointerPattern():
-    p = re.compile('[_\w\s]*\([\w\s]*\*+\s*[_\w]+\s*\)\s*\(.*\)', re.DOTALL)
+    p = re.compile(r'[_\w\s]*\([\w\s]*\*+\s*[_\w]+\s*\)\s*\(.*\)', re.DOTALL)
     return p
 
 def GetDB():
diff --git a/BaseTools/Source/Python/Eot/EotGlobalData.py b/BaseTools/Source/Python/Eot/EotGlobalData.py
index 3218f86f44..2bec8b0b18 100644
--- a/BaseTools/Source/Python/Eot/EotGlobalData.py
+++ b/BaseTools/Source/Python/Eot/EotGlobalData.py
@@ -11,7 +11,7 @@ from Common.LongFilePathSupport import OpenLongFilePath as open
 gEFI_SOURCE = ''
 gEDK_SOURCE = ''
 gWORKSPACE = ''
-gSHELL_INF = 'Application\Shell'
+gSHELL_INF = 'Application\\Shell'
 gMAKE_FILE = ''
 gDSC_FILE = ''
 gFV_FILE = []
diff --git a/BaseTools/Source/Python/Eot/c.py b/BaseTools/Source/Python/Eot/c.py
index dd9530fed6..a85564d600 100644
--- a/BaseTools/Source/Python/Eot/c.py
+++ b/BaseTools/Source/Python/Eot/c.py
@@ -54,7 +54,7 @@ def GetArrayPattern():
 #  @return p:    the pattern of function pointer
 #
 def GetTypedefFuncPointerPattern():
-    p = re.compile('[_\w\s]*\([\w\s]*\*+\s*[_\w]+\s*\)\s*\(.*\)', re.DOTALL)
+    p = re.compile(r'[_\w\s]*\([\w\s]*\*+\s*[_\w]+\s*\)\s*\(.*\)', re.DOTALL)
     return p
 
 ## GetDB() method
diff --git a/BaseTools/Source/Python/UPT/Library/CommentParsing.py b/BaseTools/Source/Python/UPT/Library/CommentParsing.py
index 7ba9830d34..7b1ce05493 100644
--- a/BaseTools/Source/Python/UPT/Library/CommentParsing.py
+++ b/BaseTools/Source/Python/UPT/Library/CommentParsing.py
@@ -238,7 +238,7 @@ def ParseDecPcdGenericComment (GenericComment, ContainerFile, TokenSpaceGuidCNam
         #
         # To replace Macro
         #
-        MACRO_PATTERN = '[\t\s]*\$\([A-Z][_A-Z0-9]*\)'
+        MACRO_PATTERN = r'[\t\s]*\$\([A-Z][_A-Z0-9]*\)'
         MatchedStrs =  re.findall(MACRO_PATTERN, Comment)
         for MatchedStr in MatchedStrs:
             if MatchedStr:
diff --git a/BaseTools/Source/Python/UPT/Library/ExpressionValidate.py b/BaseTools/Source/Python/UPT/Library/ExpressionValidate.py
index 7718ca12e5..2c0750efe4 100644
--- a/BaseTools/Source/Python/UPT/Library/ExpressionValidate.py
+++ b/BaseTools/Source/Python/UPT/Library/ExpressionValidate.py
@@ -66,13 +66,13 @@ class _ExprError(Exception):
 ## _ExprBase
 #
 class _ExprBase:
-    HEX_PATTERN = '[\t\s]*0[xX][a-fA-F0-9]+'
-    INT_PATTERN = '[\t\s]*[0-9]+'
-    MACRO_PATTERN = '[\t\s]*\$\(([A-Z][_A-Z0-9]*)\)'
+    HEX_PATTERN = r'[\t\s]*0[xX][a-fA-F0-9]+'
+    INT_PATTERN = r'[\t\s]*[0-9]+'
+    MACRO_PATTERN = r'[\t\s]*\$\(([A-Z][_A-Z0-9]*)\)'
     PCD_PATTERN = \
-    '[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*\.[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*'
-    QUOTED_PATTERN = '[\t\s]*L?"[^"]*"'
-    BOOL_PATTERN = '[\t\s]*(true|True|TRUE|false|False|FALSE)'
+    r'[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*\.[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*'
+    QUOTED_PATTERN = r'[\t\s]*L?"[^"]*"'
+    BOOL_PATTERN = r'[\t\s]*(true|True|TRUE|false|False|FALSE)'
     def __init__(self, Token):
         self.Token = Token
         self.Index = 0
@@ -303,9 +303,9 @@ class _LogicalExpressionParser(_ExprBase):
 ## _ValidRangeExpressionParser
 #
 class _ValidRangeExpressionParser(_ExprBase):
-    INT_RANGE_PATTERN = '[\t\s]*[0-9]+[\t\s]*-[\t\s]*[0-9]+'
+    INT_RANGE_PATTERN = r'[\t\s]*[0-9]+[\t\s]*-[\t\s]*[0-9]+'
     HEX_RANGE_PATTERN = \
-        '[\t\s]*0[xX][a-fA-F0-9]+[\t\s]*-[\t\s]*0[xX][a-fA-F0-9]+'
+        r'[\t\s]*0[xX][a-fA-F0-9]+[\t\s]*-[\t\s]*0[xX][a-fA-F0-9]+'
     def __init__(self, Token):
         _ExprBase.__init__(self, Token)
         self.Parens = 0
@@ -407,7 +407,7 @@ class _ValidRangeExpressionParser(_ExprBase):
 ## _ValidListExpressionParser
 #
 class _ValidListExpressionParser(_ExprBase):
-    VALID_LIST_PATTERN = '(0[xX][0-9a-fA-F]+|[0-9]+)([\t\s]*,[\t\s]*(0[xX][0-9a-fA-F]+|[0-9]+))*'
+    VALID_LIST_PATTERN = r'(0[xX][0-9a-fA-F]+|[0-9]+)([\t\s]*,[\t\s]*(0[xX][0-9a-fA-F]+|[0-9]+))*'
     def __init__(self, Token):
         _ExprBase.__init__(self, Token)
         self.NUM = 1
diff --git a/BaseTools/Source/Python/UPT/Library/Misc.py b/BaseTools/Source/Python/UPT/Library/Misc.py
index 77ba3584e0..94ca4456e8 100644
--- a/BaseTools/Source/Python/UPT/Library/Misc.py
+++ b/BaseTools/Source/Python/UPT/Library/Misc.py
@@ -69,11 +69,11 @@ def GuidStringToGuidStructureString(Guid):
 def CheckGuidRegFormat(GuidValue):
     ## Regular expression used to find out register format of GUID
     #
-    RegFormatGuidPattern = re.compile("^\s*([0-9a-fA-F]){8}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){12}\s*$")
+    RegFormatGuidPattern = re.compile(r"^\s*([0-9a-fA-F]){8}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){12}\s*$")
 
     if RegFormatGuidPattern.match(GuidValue):
         return True
@@ -837,8 +837,8 @@ def GetLibInstanceInfo(String, WorkSpace, LineNo):
                          ST.ERR_FILE_OPEN_FAILURE,
                          File=FullFileName)
 
-        ReFileGuidPattern = re.compile("^\s*FILE_GUID\s*=.*$")
-        ReVerStringPattern = re.compile("^\s*VERSION_STRING\s*=.*$")
+        ReFileGuidPattern = re.compile(r"^\s*FILE_GUID\s*=.*$")
+        ReVerStringPattern = re.compile(r"^\s*VERSION_STRING\s*=.*$")
 
         FileLinesList = ProcessLineExtender(FileLinesList)
 
@@ -978,7 +978,7 @@ def ValidateUNIFilePath(Path):
     #
     # Check if the file name is valid according to the DEC and INF specification
     #
-    Pattern = '[a-zA-Z0-9_][a-zA-Z0-9_\-\.]*'
+    Pattern = r'[a-zA-Z0-9_][a-zA-Z0-9_\-\.]*'
     FileName = Path.replace(Suffix, '')
     InvalidCh = re.sub(Pattern, '', FileName)
     if InvalidCh:
diff --git a/BaseTools/Source/Python/UPT/Library/StringUtils.py b/BaseTools/Source/Python/UPT/Library/StringUtils.py
index fbc5177caf..a5d73c5a6f 100644
--- a/BaseTools/Source/Python/UPT/Library/StringUtils.py
+++ b/BaseTools/Source/Python/UPT/Library/StringUtils.py
@@ -23,7 +23,7 @@ from Logger import StringTable as ST
 #
 # Regular expression for matching macro used in DSC/DEC/INF file inclusion
 #
-gMACRO_PATTERN = re.compile("\$\(([_A-Z][_A-Z0-9]*)\)", re.UNICODE)
+gMACRO_PATTERN = re.compile(r"\$\(([_A-Z][_A-Z0-9]*)\)", re.UNICODE)
 
 ## GetSplitValueList
 #
@@ -167,7 +167,7 @@ def ReplaceMacro(String, MacroDefinitions=None, SelfReplacement=False, Line=None
         if not Flag:
             MacroUsed = gMACRO_PATTERN.findall(String)
         else:
-            ReQuotedString = re.compile('\"')
+            ReQuotedString = re.compile(r'\"')
             QuotedStringList = ReQuotedString.split(String)
             if len(QuotedStringList) >= 3:
                 HaveQuotedMacroFlag = True
diff --git a/BaseTools/Source/Python/UPT/Object/Parser/InfPcdObject.py b/BaseTools/Source/Python/UPT/Object/Parser/InfPcdObject.py
index fd8065fab5..b6e407406b 100644
--- a/BaseTools/Source/Python/UPT/Object/Parser/InfPcdObject.py
+++ b/BaseTools/Source/Python/UPT/Object/Parser/InfPcdObject.py
@@ -611,10 +611,10 @@ def ValidatePcdValueOnDatumType(Value, Type):
 
     elif Type == 'UINT8' or Type == 'UINT16' or Type == 'UINT32' or Type == 'UINT64':
 
-        ReIsValidUint8z = re.compile('^0[x|X][a-fA-F0-9]{2}$')
-        ReIsValidUint16z = re.compile('^0[x|X][a-fA-F0-9]{4}$')
-        ReIsValidUint32z = re.compile('^0[x|X][a-fA-F0-9]{8}$')
-        ReIsValidUint64z = re.compile('^0[x|X][a-fA-F0-9]{16}$')
+        ReIsValidUint8z = re.compile(r'^0[x|X][a-fA-F0-9]{2}$')
+        ReIsValidUint16z = re.compile(r'^0[x|X][a-fA-F0-9]{4}$')
+        ReIsValidUint32z = re.compile(r'^0[x|X][a-fA-F0-9]{8}$')
+        ReIsValidUint64z = re.compile(r'^0[x|X][a-fA-F0-9]{16}$')
 
         if not ReIsValidUint8z.match(Value) and Type == 'UINT8':
             return False
diff --git a/BaseTools/Source/Python/UPT/Parser/DecParserMisc.py b/BaseTools/Source/Python/UPT/Parser/DecParserMisc.py
index 27990467d1..98ccc8f7a4 100644
--- a/BaseTools/Source/Python/UPT/Parser/DecParserMisc.py
+++ b/BaseTools/Source/Python/UPT/Parser/DecParserMisc.py
@@ -25,10 +25,10 @@ from Library.ExpressionValidate import IsValidStringTest
 from Library.Misc import CheckGuidRegFormat
 
 TOOL_NAME = 'DecParser'
-VERSION_PATTERN = '[0-9]+(\.[0-9]+)?'
-CVAR_PATTERN = '[_a-zA-Z][a-zA-Z0-9_]*'
-PCD_TOKEN_PATTERN = '(0[xX]0*[a-fA-F0-9]{1,8})|([0-9]+)'
-MACRO_PATTERN = '[A-Z][_A-Z0-9]*'
+VERSION_PATTERN = r'[0-9]+(\.[0-9]+)?'
+CVAR_PATTERN = r'[_a-zA-Z][a-zA-Z0-9_]*'
+PCD_TOKEN_PATTERN = r'(0[xX]0*[a-fA-F0-9]{1,8})|([0-9]+)'
+MACRO_PATTERN = r'[A-Z][_A-Z0-9]*'
 
 ## FileContent
 # Class to hold DEC file information
diff --git a/BaseTools/Source/Python/UPT/Parser/InfAsBuiltProcess.py b/BaseTools/Source/Python/UPT/Parser/InfAsBuiltProcess.py
index 992b609120..9480a5e168 100644
--- a/BaseTools/Source/Python/UPT/Parser/InfAsBuiltProcess.py
+++ b/BaseTools/Source/Python/UPT/Parser/InfAsBuiltProcess.py
@@ -53,12 +53,12 @@ def GetLibInstanceInfo(String, WorkSpace, LineNo, CurrentInfFileName):
     #
     # To deal with library instance specified by GUID and version
     #
-    RegFormatGuidPattern = re.compile("\s*([0-9a-fA-F]){8}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){4}-"
-                                       "([0-9a-fA-F]){12}\s*")
-    VersionPattern = re.compile('[\t\s]*\d+(\.\d+)?[\t\s]*')
+    RegFormatGuidPattern = re.compile(r"\s*([0-9a-fA-F]){8}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){4}-"
+                                       r"([0-9a-fA-F]){12}\s*")
+    VersionPattern = re.compile(r'[\t\s]*\d+(\.\d+)?[\t\s]*')
     GuidMatchedObj = RegFormatGuidPattern.search(String)
 
     if String.upper().startswith('GUID') and GuidMatchedObj and 'Version' in String:
@@ -75,8 +75,8 @@ def GetLibInstanceInfo(String, WorkSpace, LineNo, CurrentInfFileName):
     FileLinesList = GetFileLineContent(String, WorkSpace, LineNo, OriginalString)
 
 
-    ReFindFileGuidPattern = re.compile("^\s*FILE_GUID\s*=.*$")
-    ReFindVerStringPattern = re.compile("^\s*VERSION_STRING\s*=.*$")
+    ReFindFileGuidPattern = re.compile(r"^\s*FILE_GUID\s*=.*$")
+    ReFindVerStringPattern = re.compile(r"^\s*VERSION_STRING\s*=.*$")
 
     for Line in FileLinesList:
         if ReFindFileGuidPattern.match(Line):
@@ -106,8 +106,8 @@ def GetPackageListInfo(FileNameString, WorkSpace, LineNo):
 
     FileLinesList = GetFileLineContent(FileNameString, WorkSpace, LineNo, '')
 
-    RePackageHeader = re.compile('^\s*\[Packages.*\].*$')
-    ReDefineHeader = re.compile('^\s*\[Defines].*$')
+    RePackageHeader = re.compile(r'^\s*\[Packages.*\].*$')
+    ReDefineHeader = re.compile(r'^\s*\[Defines].*$')
 
     PackageHederFlag = False
     DefineHeaderFlag = False
@@ -255,8 +255,8 @@ def GetGuidVerFormLibInstance(Guid, Version, WorkSpace, CurrentInfFileName):
             FileLinesList = InfFileObj.readlines()
             FileLinesList = ProcessLineExtender(FileLinesList)
 
-            ReFindFileGuidPattern = re.compile("^\s*FILE_GUID\s*=.*$")
-            ReFindVerStringPattern = re.compile("^\s*VERSION_STRING\s*=.*$")
+            ReFindFileGuidPattern = re.compile(r"^\s*FILE_GUID\s*=.*$")
+            ReFindVerStringPattern = re.compile(r"^\s*VERSION_STRING\s*=.*$")
 
             for Line in FileLinesList:
                 if ReFindFileGuidPattern.match(Line):
diff --git a/BaseTools/Source/Python/UPT/Parser/InfDefineSectionParser.py b/BaseTools/Source/Python/UPT/Parser/InfDefineSectionParser.py
index a63e40e617..9edcc2cb3f 100644
--- a/BaseTools/Source/Python/UPT/Parser/InfDefineSectionParser.py
+++ b/BaseTools/Source/Python/UPT/Parser/InfDefineSectionParser.py
@@ -40,7 +40,7 @@ def GetValidateArchList(LineContent):
 
         TempArch = GetSplitValueList(TempArch, '(', 1)[0]
 
-        ArchList = re.split('\s+', TempArch)
+        ArchList = re.split(r'\s+', TempArch)
         NewArchList = []
         for Arch in ArchList:
             if IsValidArch(Arch):
diff --git a/BaseTools/Source/Python/UPT/Parser/InfParserMisc.py b/BaseTools/Source/Python/UPT/Parser/InfParserMisc.py
index d01ae9aa02..eb768b9a12 100644
--- a/BaseTools/Source/Python/UPT/Parser/InfParserMisc.py
+++ b/BaseTools/Source/Python/UPT/Parser/InfParserMisc.py
@@ -109,7 +109,7 @@ def InfExpandMacro(Content, LineInfo, GlobalMacros=None, SectionMacros=None, Fla
         return Content
     else:
         for Macro in MacroUsed:
-            gQuotedMacro = re.compile(".*\".*\$\(%s\).*\".*"%(Macro))
+            gQuotedMacro = re.compile(r".*\".*\$\(%s\).*\".*"%(Macro))
             if not gQuotedMacro.match(Content):
                 #
                 # Still have MACROs can't be expanded.
@@ -130,8 +130,8 @@ def IsBinaryInf(FileLineList):
     if not FileLineList:
         return False
 
-    ReIsSourcesSection = re.compile("^\s*\[Sources.*\]\s.*$", re.IGNORECASE)
-    ReIsBinarySection = re.compile("^\s*\[Binaries.*\]\s.*$", re.IGNORECASE)
+    ReIsSourcesSection = re.compile(r"^\s*\[Sources.*\]\s.*$", re.IGNORECASE)
+    ReIsBinarySection = re.compile(r"^\s*\[Binaries.*\]\s.*$", re.IGNORECASE)
     BinarySectionFoundFlag = False
 
     for Line in FileLineList:
@@ -155,7 +155,7 @@ def IsBinaryInf(FileLineList):
 # @return Flag
 #
 def IsLibInstanceInfo(String):
-    ReIsLibInstance = re.compile("^\s*##\s*@LIB_INSTANCES\s*$")
+    ReIsLibInstance = re.compile(r"^\s*##\s*@LIB_INSTANCES\s*$")
     if ReIsLibInstance.match(String):
         return True
     else:
@@ -171,7 +171,7 @@ def IsLibInstanceInfo(String):
 # @return Flag
 #
 def IsAsBuildOptionInfo(String):
-    ReIsAsBuildInstance = re.compile("^\s*##\s*@AsBuilt\s*$")
+    ReIsAsBuildInstance = re.compile(r"^\s*##\s*@AsBuilt\s*$")
     if ReIsAsBuildInstance.match(String):
         return True
     else:
diff --git a/BaseTools/Source/Python/UPT/PomAdapter/DecPomAlignment.py b/BaseTools/Source/Python/UPT/PomAdapter/DecPomAlignment.py
index da92fe5d3e..b1f8135bc7 100644
--- a/BaseTools/Source/Python/UPT/PomAdapter/DecPomAlignment.py
+++ b/BaseTools/Source/Python/UPT/PomAdapter/DecPomAlignment.py
@@ -747,12 +747,12 @@ class DecPomAlignment(PackageObject):
         #
         # deal with "NOT EQ", "NOT LT", "NOT GT", "NOT LE", "NOT GE", "NOT NOT"
         #
-        NOTNOT_Pattern = '[\t\s]*NOT[\t\s]+NOT[\t\s]*'
-        NOTGE_Pattern = '[\t\s]*NOT[\t\s]+GE[\t\s]*'
-        NOTLE_Pattern = '[\t\s]*NOT[\t\s]+LE[\t\s]*'
-        NOTGT_Pattern = '[\t\s]*NOT[\t\s]+GT[\t\s]*'
-        NOTLT_Pattern = '[\t\s]*NOT[\t\s]+LT[\t\s]*'
-        NOTEQ_Pattern = '[\t\s]*NOT[\t\s]+EQ[\t\s]*'
+        NOTNOT_Pattern = r'[\t\s]*NOT[\t\s]+NOT[\t\s]*'
+        NOTGE_Pattern = r'[\t\s]*NOT[\t\s]+GE[\t\s]*'
+        NOTLE_Pattern = r'[\t\s]*NOT[\t\s]+LE[\t\s]*'
+        NOTGT_Pattern = r'[\t\s]*NOT[\t\s]+GT[\t\s]*'
+        NOTLT_Pattern = r'[\t\s]*NOT[\t\s]+LT[\t\s]*'
+        NOTEQ_Pattern = r'[\t\s]*NOT[\t\s]+EQ[\t\s]*'
         ReplaceValue = re.compile(NOTNOT_Pattern).sub('', ReplaceValue)
         ReplaceValue = re.compile(NOTLT_Pattern).sub('x >= ', ReplaceValue)
         ReplaceValue = re.compile(NOTGT_Pattern).sub('x <= ', ReplaceValue)
@@ -785,7 +785,7 @@ class DecPomAlignment(PackageObject):
         if ReplaceValue.find('!') >= 0 and ReplaceValue[ReplaceValue.index('!') + 1] != '=':
             ReplaceValue = ReplaceValue.replace('!', ' not ')
         if '.' in ReplaceValue:
-            Pattern = '[a-zA-Z0-9]{1,}\.[a-zA-Z0-9]{1,}'
+            Pattern = r'[a-zA-Z0-9]{1,}\.[a-zA-Z0-9]{1,}'
             MatchedList = re.findall(Pattern, ReplaceValue)
             for MatchedItem in MatchedList:
                 if MatchedItem not in self.PcdDefaultValueDict:
@@ -814,7 +814,7 @@ class DecPomAlignment(PackageObject):
                     #
                     # Delete the 'L' prefix of a quoted string, this operation is for eval()
                     #
-                    QUOTED_PATTERN = '[\t\s]*L?"[^"]*"'
+                    QUOTED_PATTERN = r'[\t\s]*L?"[^"]*"'
                     QuotedMatchedObj = re.search(QUOTED_PATTERN, Expression)
                     if QuotedMatchedObj:
                         MatchedStr = QuotedMatchedObj.group().strip()
@@ -847,7 +847,7 @@ class DecPomAlignment(PackageObject):
             #
             # Delete the 'L' prefix of a quoted string, this operation is for eval()
             #
-            QUOTED_PATTERN = '[\t\s]*L?"[^"]*"'
+            QUOTED_PATTERN = r'[\t\s]*L?"[^"]*"'
             QuotedMatchedObj = re.search(QUOTED_PATTERN, DefaultValue)
             if QuotedMatchedObj:
                 MatchedStr = QuotedMatchedObj.group().strip()
diff --git a/BaseTools/Source/Python/UPT/Xml/IniToXml.py b/BaseTools/Source/Python/UPT/Xml/IniToXml.py
index 3dc4001313..2c01c97fa5 100644
--- a/BaseTools/Source/Python/UPT/Xml/IniToXml.py
+++ b/BaseTools/Source/Python/UPT/Xml/IniToXml.py
@@ -200,9 +200,9 @@ def ValidateRegValues(Key, Value):
             ('[a-fA-F0-9]{8}-[a-fA-F0-9]{4}-[a-fA-F0-9]{4}'
             '-[a-fA-F0-9]{4}-[a-fA-F0-9]{12}',
             ST.ERR_GUID_VALUE % Value),
-        'Version'   :   ('[0-9]+(\.[0-9]+)?', ST.ERR_VERSION_VALUE % \
+        'Version'   :   (r'[0-9]+(\.[0-9]+)?', ST.ERR_VERSION_VALUE % \
                          (Key, Value)),
-        'XmlSpecification' : ('1\.1', ST.ERR_VERSION_XMLSPEC % Value)
+        'XmlSpecification' : (r'1\.1', ST.ERR_VERSION_XMLSPEC % Value)
     }
     if Key not in ValidateMap:
         return True, ''
diff --git a/BaseTools/Source/Python/UPT/Xml/PcdXml.py b/BaseTools/Source/Python/UPT/Xml/PcdXml.py
index bbcee45a01..ca95c820c9 100644
--- a/BaseTools/Source/Python/UPT/Xml/PcdXml.py
+++ b/BaseTools/Source/Python/UPT/Xml/PcdXml.py
@@ -100,11 +100,11 @@ class PcdErrorXml(object):
     def TransferValidRange2Expr(self, TokenSpaceGuidCName, CName, ValidRange):
         if self.Expression:
             pass
-        INT_RANGE_PATTERN1 = '[\t\s]*[0-9]+[\t\s]*-[\t\s]*[0-9]+'
-        INT_RANGE_PATTERN2 = '[\t\s]*(LT|GT|LE|GE|XOR|EQ)[\t\s]+\d+[\t\s]*'
+        INT_RANGE_PATTERN1 = r'[\t\s]*[0-9]+[\t\s]*-[\t\s]*[0-9]+'
+        INT_RANGE_PATTERN2 = r'[\t\s]*(LT|GT|LE|GE|XOR|EQ)[\t\s]+\d+[\t\s]*'
         HEX_RANGE_PATTERN1 = \
-            '[\t\s]*0[xX][a-fA-F0-9]+[\t\s]*-[\t\s]*0[xX][a-fA-F0-9]+'
-        HEX_RANGE_PATTERN2 = '[\t\s]*(LT|GT|LE|GE|XOR|EQ)[\t\s]+0[xX][a-fA-F0-9]+[\t\s]*'
+            r'[\t\s]*0[xX][a-fA-F0-9]+[\t\s]*-[\t\s]*0[xX][a-fA-F0-9]+'
+        HEX_RANGE_PATTERN2 = r'[\t\s]*(LT|GT|LE|GE|XOR|EQ)[\t\s]+0[xX][a-fA-F0-9]+[\t\s]*'
         IntMatch1 = re.compile(INT_RANGE_PATTERN1)
         IntMatch2 = re.compile(INT_RANGE_PATTERN2)
         HexMatch1 = re.compile(HEX_RANGE_PATTERN1)
@@ -158,18 +158,18 @@ class PcdErrorXml(object):
             pass
 
         PCD_PATTERN = \
-        '[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*\.[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*'
+        r'[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*\.[\t\s]*[_a-zA-Z][a-zA-Z0-9_]*[\t\s]*'
         IntPattern1 = \
-        '[\t\s]*\([\t\s]*'+PCD_PATTERN+'[\t\s]+GE[\t\s]+\d+[\t\s]*\)[\t\s]+AND[\t\s]+\([\t\s]*'+\
-        PCD_PATTERN+'[\t\s]+LE[\t\s]+\d+[\t\s]*\)'
+        r'[\t\s]*\([\t\s]*'+PCD_PATTERN+r'[\t\s]+GE[\t\s]+\d+[\t\s]*\)[\t\s]+AND[\t\s]+\([\t\s]*'+\
+        PCD_PATTERN+r'[\t\s]+LE[\t\s]+\d+[\t\s]*\)'
         IntPattern1 = IntPattern1.replace(' ', '')
-        IntPattern2 = '[\t\s]*'+PCD_PATTERN+'[\t\s]+(LT|GT|LE|GE|XOR|EQ)[\t\s]+\d+[\t\s]*'
+        IntPattern2 = r'[\t\s]*'+PCD_PATTERN+r'[\t\s]+(LT|GT|LE|GE|XOR|EQ)[\t\s]+\d+[\t\s]*'
 
         HexPattern1 = \
-        '[\t\s]*\([\t\s]*'+PCD_PATTERN+'[\t\s]+GE[\t\s]+0[xX][0-9a-fA-F]+[\t\s]*\)[\t\s]+AND[\t\s]+\([\t\s]*'+\
-        PCD_PATTERN+'[\t\s]+LE[\t\s]+0[xX][0-9a-fA-F]+[\t\s]*\)'
+        r'[\t\s]*\([\t\s]*'+PCD_PATTERN+r'[\t\s]+GE[\t\s]+0[xX][0-9a-fA-F]+[\t\s]*\)[\t\s]+AND[\t\s]+\([\t\s]*'+\
+        PCD_PATTERN+r'[\t\s]+LE[\t\s]+0[xX][0-9a-fA-F]+[\t\s]*\)'
         HexPattern1 = HexPattern1.replace(' ', '')
-        HexPattern2 = '[\t\s]*'+PCD_PATTERN+'[\t\s]+(LT|GT|LE|GE|XOR|EQ)[\t\s]+0[xX][0-9a-zA-Z]+[\t\s]*'
+        HexPattern2 = r'[\t\s]*'+PCD_PATTERN+r'[\t\s]+(LT|GT|LE|GE|XOR|EQ)[\t\s]+0[xX][0-9a-zA-Z]+[\t\s]*'
 
         #
         # Do the Hex1 conversion
@@ -180,7 +180,7 @@ class PcdErrorXml(object):
             #
             # To match items on both sides of '-'
             #
-            RangeItemList = re.compile('[\t\s]*0[xX][0-9a-fA-F]+[\t\s]*').findall(HexMatchedItem)
+            RangeItemList = re.compile(r'[\t\s]*0[xX][0-9a-fA-F]+[\t\s]*').findall(HexMatchedItem)
             if RangeItemList and len(RangeItemList) == 2:
                 HexRangeDict[HexMatchedItem] = RangeItemList
 
@@ -204,7 +204,7 @@ class PcdErrorXml(object):
             #
             # To match items on both sides of '-'
             #
-            RangeItemList = re.compile('[\t\s]*\d+[\t\s]*').findall(MatchedItem)
+            RangeItemList = re.compile(r'[\t\s]*\d+[\t\s]*').findall(MatchedItem)
             if RangeItemList and len(RangeItemList) == 2:
                 IntRangeDict[MatchedItem] = RangeItemList
 
diff --git a/BaseTools/Source/Python/UPT/Xml/XmlParser.py b/BaseTools/Source/Python/UPT/Xml/XmlParser.py
index 8e22a280f6..f239588831 100644
--- a/BaseTools/Source/Python/UPT/Xml/XmlParser.py
+++ b/BaseTools/Source/Python/UPT/Xml/XmlParser.py
@@ -281,33 +281,33 @@ class DistributionPackageXml(object):
             #
             XmlContent = \
             re.sub(r'[\s\r\n]*SupArchList[\s\r\n]*=[\s\r\n]*"[\s\r\n]*COMMON'
-            '[\s\r\n]*"', '', XmlContent)
+            r'[\s\r\n]*"', '', XmlContent)
             XmlContent = \
             re.sub(r'[\s\r\n]*SupArchList[\s\r\n]*=[\s\r\n]*"[\s\r\n]*common'
-            '[\s\r\n]*"', '', XmlContent)
+            r'[\s\r\n]*"', '', XmlContent)
             #
             # Remove <SupArchList> COMMON </SupArchList>
             #
             XmlContent = \
             re.sub(r'[\s\r\n]*<SupArchList>[\s\r\n]*COMMON[\s\r\n]*'
-            '</SupArchList>[\s\r\n]*', '', XmlContent)
+            r'</SupArchList>[\s\r\n]*', '', XmlContent)
 
             #
             # Remove <SupArchList> common </SupArchList>
             #
             XmlContent = \
             re.sub(r'[\s\r\n]*<SupArchList>[\s\r\n]*'
-            'common[\s\r\n]*</SupArchList>[\s\r\n]*', '', XmlContent)
+            r'common[\s\r\n]*</SupArchList>[\s\r\n]*', '', XmlContent)
 
             #
             # Remove SupModList="COMMON" or "common"
             #
             XmlContent = \
             re.sub(r'[\s\r\n]*SupModList[\s\r\n]*=[\s\r\n]*"[\s\r\n]*COMMON'
-            '[\s\r\n]*"', '', XmlContent)
+            r'[\s\r\n]*"', '', XmlContent)
             XmlContent = \
             re.sub(r'[\s\r\n]*SupModList[\s\r\n]*=[\s\r\n]*"[\s\r\n]*common'
-            '[\s\r\n]*"', '', XmlContent)
+            r'[\s\r\n]*"', '', XmlContent)
 
             return XmlContent