diff --git a/MdePkg/Include/IndustryStandard/PldmSmbiosTransfer.h b/MdePkg/Include/IndustryStandard/PldmSmbiosTransfer.h
new file mode 100644
index 0000000000..9b7a5e838e
--- /dev/null
+++ b/MdePkg/Include/IndustryStandard/PldmSmbiosTransfer.h
@@ -0,0 +1,183 @@
+/** @file
+
+  The definitions of DMTF Platform Level Data Model (PLDM)
+  SMBIOS Transfer Specification.
+
+  Copyright (C) 2023 Advanced Micro Devices, Inc. All rights reserved.
+  SPDX-License-Identifier: BSD-2-Clause-Patent
+
+  @par Revision Reference:
+  DMTF Platform Level Data Model (PLDM) SMBIOS Transfer Specification
+  Version 1.0.1
+  https://www.dmtf.org/sites/default/files/standards/documents/DSP0246_1.0.1.pdf
+
+**/
+
+#ifndef PLDM_SMBIOS_TRANSFER_H_
+#define PLDM_SMBIOS_TRANSFER_H_
+
+#include <IndustryStandard/Pldm.h>
+
+#pragma pack(1)
+
+///
+/// Smbios-related definitions from PLDM for SMBIOS Transfer
+/// Specification (DMTF DSP0246)
+///
+#define PLDM_GET_SMBIOS_STRUCTURE_TABLE_METADATA_COMMAND_CODE  0x01
+#define PLDM_SET_SMBIOS_STRUCTURE_TABLE_METADATA_COMMAND_CODE  0x02
+#define PLDM_GET_SMBIOS_STRUCTURE_TABLE_COMMAND_CODE           0x03
+#define PLDM_SET_SMBIOS_STRUCTURE_TABLE_COMMAND_CODE           0x04
+#define PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_COMMAND_CODE         0x05
+#define PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_COMMAND_CODE       0x06
+
+///
+/// PLDM SMBIOS transfer command specific completion code.
+///
+#define PLDM_COMPLETION_CODE_INVALID_DATA_TRANSFER_HANDLE        0x80
+#define PLDM_COMPLETION_CODE_INVALID_TRANSFER_OPERATION_FLAG     0x81
+#define PLDM_COMPLETION_CODE_INVALID_TRANSFER_FLAG               0x82
+#define PLDM_COMPLETION_CODE_NO_SMBIOS_STRUCTURE_TABLE_METADATA  0x83
+#define PLDM_COMPLETION_CODE_INVALID_DATA_INTEGRITY_CHECK        0x84
+#define PLDM_COMPLETION_CODE_SMBIOS_STRUCTURE_TABLE_UNAVAILABLE  0x85
+
+///
+/// Get SMBIOS Structure Table Metadata Response.
+///
+typedef struct {
+  UINT8     SmbiosMajorVersion;
+  UINT8     SmbiosMinorVersion;
+  UINT16    MaximumStructureSize;
+  UINT16    SmbiosStructureTableLength;
+  UINT16    NumberOfSmbiosStructures;
+  UINT32    SmbiosStructureTableIntegrityChecksum;
+} PLDM_SMBIOS_STRUCTURE_TABLE_METADATA;
+
+typedef struct {
+  PLDM_RESPONSE_HEADER                    ResponseHeader;
+  PLDM_SMBIOS_STRUCTURE_TABLE_METADATA    SmbiosStructureTableMetadata;
+} PLDM_GET_SMBIOS_STRUCTURE_TABLE_METADATA_RESPONSE_FORMAT;
+
+///
+/// Set SMBIOS Structure Table Metadata Request.
+///
+typedef struct {
+  PLDM_REQUEST_HEADER                     RequestHeader;
+  PLDM_SMBIOS_STRUCTURE_TABLE_METADATA    SmbiosStructureTableMetadata;
+} PLDM_SET_SMBIOS_STRUCTURE_TABLE_METADATA_REQUEST_FORMAT;
+
+///
+/// Set SMBIOS Structure Table Metadata Response.
+///
+typedef struct {
+  PLDM_RESPONSE_HEADER    ResponseHeader;
+} PLDM_SET_SMBIOS_STRUCTURE_TABLE_METADATA_RESPONSE_FORMAT;
+
+///
+/// Get SMBIOS Structure Table Request.
+///
+typedef struct {
+  UINT32    DataTransferHandle;
+  UINT8     TransferOperationFlag;
+} PLDM_GET_SMBIOS_STRUCTURE_TABLE_REQUEST;
+
+typedef struct {
+  PLDM_REQUEST_HEADER                        RequestHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_TABLE_REQUEST    GetSmbiosStructureTableRequest;
+} PLDM_GET_SMBIOS_STRUCTURE_TABLE_REQUEST_FORMAT;
+
+///
+/// Get SMBIOS Structure Table Response.
+///
+typedef struct {
+  UINT32    NextDataTransferHandle;
+  UINT8     TransferFlag;
+  UINT8     Table[0];
+} PLDM_GET_SMBIOS_STRUCTURE_TABLE_RESPONSE;
+
+typedef struct {
+  PLDM_RESPONSE_HEADER                        ResponseHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_TABLE_RESPONSE    GetSmbiosStructureTableResponse;
+} PLDM_GET_SMBIOS_STRUCTURE_TABLE_RESPONSE_FORMAT;
+
+///
+/// Set SMBIOS Structure Table Request.
+///
+typedef struct {
+  UINT32    DataTransferHandle;
+  UINT8     TransferFlag;
+  UINT8     Table[0];
+} PLDM_SET_SMBIOS_STRUCTURE_TABLE_REQUEST;
+
+typedef struct {
+  PLDM_REQUEST_HEADER                        RequestHeader;
+  PLDM_SET_SMBIOS_STRUCTURE_TABLE_REQUEST    SetSmbiosStructureTableRequest;
+} PLDM_SET_SMBIOS_STRUCTURE_TABLE_REQUEST_FORMAT;
+
+///
+/// Set SMBIOS Structure Table Response.
+///
+typedef struct {
+  PLDM_RESPONSE_HEADER    ResponseHeader;
+  UINT32                  NextDataTransferHandle;
+} PLDM_SET_SMBIOS_STRUCTURE_TABLE_RESPONSE_FORMAT;
+
+///
+/// Get SMBIOS Structure by Type Request.
+///
+typedef struct {
+  UINT32    DataTransferHandle;
+  UINT8     TransferOperationFlag;
+  UINT8     Type;
+  UINT16    StructureInstanceId;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_REQUEST;
+
+typedef struct {
+  PLDM_REQUEST_HEADER                          RequestHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_REQUEST    GetSmbiosStructureByTypeRequest;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_REQUEST_FORMAT;
+
+///
+/// Get SMBIOS Structure by Type Response.
+///
+typedef struct {
+  UINT32    NextDataTransferHandle;
+  UINT8     TransferFlag;
+  UINT8     Table[0];
+} PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_RESPONSE;
+
+typedef struct {
+  PLDM_RESPONSE_HEADER                          ResponseHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_RESPONSE    GetSmbiosStructureByTypeResponse;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_TYPE_RESPONSE_FORMAT;
+
+///
+/// Get SMBIOS Structure by Handle Request.
+///
+typedef struct {
+  UINT32    DataTransferHandle;
+  UINT8     TransferOperationFlag;
+  UINT16    Handle;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_REQUEST;
+
+typedef struct {
+  PLDM_REQUEST_HEADER                            RequestHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_REQUEST    GetSmbiosStructureByHandleRequest;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_REQUEST_FORMAT;
+
+///
+/// Get SMBIOS Structure by Handle Response.
+///
+typedef struct {
+  UINT32    NextDataTransferHandle;
+  UINT8     TransferFlag;
+  UINT8     Table[0];
+} PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_RESPONSE;
+
+typedef struct {
+  PLDM_RESPONSE_HEADER                            ResponseHeader;
+  PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_RESPONSE    GetSmbiosStructureByTypeResponse;
+} PLDM_GET_SMBIOS_STRUCTURE_BY_HANDLE_RESPONSE_FORMAT;
+#pragma pack()
+
+#endif // PLDM_SMBIOS_TRANSFER_H_