diff --git a/CryptoPkg/Library/Include/openssl/opensslconf.h b/CryptoPkg/Library/Include/openssl/opensslconf.h
index 2b4d538e92..bd34e53ef2 100644
--- a/CryptoPkg/Library/Include/openssl/opensslconf.h
+++ b/CryptoPkg/Library/Include/openssl/opensslconf.h
@@ -109,9 +109,6 @@ extern "C" {
 #ifndef OPENSSL_NO_ASYNC
 # define OPENSSL_NO_ASYNC
 #endif
-#ifndef OPENSSL_NO_AUTOALGINIT
-# define OPENSSL_NO_AUTOALGINIT
-#endif
 #ifndef OPENSSL_NO_AUTOERRINIT
 # define OPENSSL_NO_AUTOERRINIT
 #endif
diff --git a/CryptoPkg/Library/OpensslLib/process_files.pl b/CryptoPkg/Library/OpensslLib/process_files.pl
index 11cd58cc4e..4ba25da407 100755
--- a/CryptoPkg/Library/OpensslLib/process_files.pl
+++ b/CryptoPkg/Library/OpensslLib/process_files.pl
@@ -51,7 +51,6 @@ BEGIN {
                 "no-afalgeng",
                 "no-asm",
                 "no-async",
-                "no-autoalginit",
                 "no-autoerrinit",
                 "no-autoload-config",
                 "no-bf",