diff --git a/MdePkg/Library/BasePrintLib/PrintLibInternal.c b/MdePkg/Library/BasePrintLib/PrintLibInternal.c
index 9b15a07ac0..cec5b3bc99 100644
--- a/MdePkg/Library/BasePrintLib/PrintLibInternal.c
+++ b/MdePkg/Library/BasePrintLib/PrintLibInternal.c
@@ -653,7 +653,7 @@ BasePrintLibSPrintMarker (
   //
   // Get the first character from the format string
   //
-  FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+  FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
 
   //
   // Loop until the end of the format string is reached or the output buffer is full
@@ -685,7 +685,7 @@ BasePrintLibSPrintMarker (
       //
       for (Done = FALSE; !Done; ) {
         Format += BytesPerFormatCharacter;
-        FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+        FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
         switch (FormatCharacter) {
         case '.': 
           Flags |= PRECISION; 
@@ -738,7 +738,7 @@ BasePrintLibSPrintMarker (
           for (Count = 0; ((FormatCharacter >= '0') &&  (FormatCharacter <= '9')); ){
             Count = (Count * 10) + FormatCharacter - '0';
             Format += BytesPerFormatCharacter;
-            FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+            FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
           }
           Format -= BytesPerFormatCharacter;
           if ((Flags & PRECISION) == 0) {
@@ -1017,7 +1017,7 @@ BasePrintLibSPrintMarker (
 
       case '\r':
         Format += BytesPerFormatCharacter;
-        FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+        FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
         if (FormatCharacter == '\n') {
           //
           // Translate '\r\n' to '\r\n'
@@ -1038,7 +1038,7 @@ BasePrintLibSPrintMarker (
         //
         ArgumentString = "\r\n";
         Format += BytesPerFormatCharacter;
-        FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+        FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
         if (FormatCharacter != '\r') {
           Format   -= BytesPerFormatCharacter;
         }
@@ -1057,7 +1057,7 @@ BasePrintLibSPrintMarker (
  
     case '\r':
       Format += BytesPerFormatCharacter;
-      FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+      FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
       if (FormatCharacter == '\n') {
         //
         // Translate '\r\n' to '\r\n'
@@ -1078,7 +1078,7 @@ BasePrintLibSPrintMarker (
       //
       ArgumentString = "\r\n";
       Format += BytesPerFormatCharacter;
-      FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+      FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
       if (FormatCharacter != '\r') {
         Format   -= BytesPerFormatCharacter;
       }
@@ -1206,7 +1206,7 @@ BasePrintLibSPrintMarker (
     //
     // Get the next character from the format string
     //
-    FormatCharacter = ((*Format & 0xff) | (*(Format + 1) << 8)) & FormatMask;
+    FormatCharacter = ((*Format & 0xff) | ((BytesPerFormatCharacter == 1) ? 0 : (*(Format + 1) << 8))) & FormatMask;
   }
 
   if ((Flags & COUNT_ONLY_NO_PRINT) != 0) {