diff --git a/MdePkg/Include/IndustryStandard/Acpi64.h b/MdePkg/Include/IndustryStandard/Acpi64.h
index 1e9634cb6d..b8be65c5e1 100644
--- a/MdePkg/Include/IndustryStandard/Acpi64.h
+++ b/MdePkg/Include/IndustryStandard/Acpi64.h
@@ -2843,11 +2843,6 @@ typedef struct {
 ///
 #define EFI_ACPI_6_4_DMA_REMAPPING_TABLE_SIGNATURE  SIGNATURE_32('D', 'M', 'A', 'R')
 
-///
-/// "DPPT" DMA Protection Policy Table
-///
-#define EFI_ACPI_6_4_DMA_PROTECTION_POLICY_TABLE_SIGNATURE  SIGNATURE_32('D', 'P', 'P', 'T')
-
 ///
 /// "DRTM" Dynamic Root of Trust for Measurement Table
 ///