diff --git a/MdePkg/Include/Library/DebugLib.h b/MdePkg/Include/Library/DebugLib.h
index 40772f2e0f..0db3b78ec8 100644
--- a/MdePkg/Include/Library/DebugLib.h
+++ b/MdePkg/Include/Library/DebugLib.h
@@ -375,9 +375,9 @@ UnitTestDebugAssert (
         DebugPrint (PrintLevel, ##__VA_ARGS__);      \
       }                                              \
     } while (FALSE)
-#define _DEBUG(Expression)  _DEBUG_PRINT Expression
+#define _DEBUGLIB_DEBUG(Expression)  _DEBUG_PRINT Expression
 #else
-#define _DEBUG(Expression)  DebugPrint Expression
+#define _DEBUGLIB_DEBUG(Expression)  DebugPrint Expression
 #endif
 
 /**
@@ -422,7 +422,7 @@ UnitTestDebugAssert (
 #define DEBUG(Expression)        \
     do {                           \
       if (DebugPrintEnabled ()) {  \
-        _DEBUG (Expression);       \
+        _DEBUGLIB_DEBUG (Expression);       \
       }                            \
     } while (FALSE)
 #else