diff --git a/MdePkg/Library/BaseLib/String.c b/MdePkg/Library/BaseLib/String.c
index 70079f7975..9a083444b3 100644
--- a/MdePkg/Library/BaseLib/String.c
+++ b/MdePkg/Library/BaseLib/String.c
@@ -822,7 +822,6 @@ StrHexToUintn (
   }
 
   if (InternalCharToUpper (*String) == L'X') {
-    ASSERT (*(String - 1) == L'0');
     if (*(String - 1) != L'0') {
       return 0;
     }